Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep882 | Growth hormone IGF axis - basic | ECE2017

Could statin modify molecular phenotype of pituitary growth hormone-secreting tumors?

Exposito Maria Rosa Alhambra , Moreno Paloma Moreno , Jimenez Concepcion Munoz , Moreno Maria Angeles Galvez , Huertas Raul Luque

Background: Acromegaly is the consequence of excessive growth hormone (GH) secretion, usually produced by a pituitary adenoma. In the last years, statins have been implicated in the response to treatment of patients with acromegaly. Although this fact is not very clear.Objective: To analyze whether pretreatment with statins modifies the adenoma molecular phenotype of the acromegalic patients and how this changes could help to influence the response to tr...